📝 Abstract
In this report we present a medically complex kidney transplant recipient with new-onset HOHF and pulmonary hypertension who improved after AVF ligation. This report highlights the importance of considering all etiologies of HOHF in a patient with unexplained edema and dyspnea, and describes the successful treatment of heart failure upon ligation of the AVF. We review the presentation, pathophysiology, and management of this disease process, and discuss an ongoing dilemma faced by clinicians in whether to pursue closure of an AVF in stable kidney transplant recipients.